Following is the list of top 10 most influential people who have proven themselves as trend-setters of the web. The list was compiled based on the information available online.
1. Mark Zuckerberg

Mark has redefined what MySpace started a few years ago and has taken social networking to a whole another level. With over 41 million registered users, Facebook has become a different world where people just ‘hang-out’ boycotting the rest of the web.
2 . Michael Arrington

Mike is the founder and editor of TechCrunch.com, one of the most popular blogs devoted to startups and new web technologies. Since Mike started TechCrunch in June of 2005, it has become a must read must-read in the fast-growing Web 2.0 world. His posts are so influential that they have been rumored to easily make or break a start-up’s success.
3. Kevin Rose

Kevin founded the famous Digg.com, a technology news website that combines social bookmarking, blogging, RSS, and non-hierarchical editorial control. Digg revolutionized the way news was read by empowering site-visitors to choose and vote on news they deemed read-worthy.
4. Larry Page and Sergey Brin

Google. Period.
5. Steve Jobs

Steve Jobs innovative thought process led him into revolutionizing the computer hardware and software industry. Apple’s latest release, Leopard, has been ranked by many critics as a far better performing OS than Vista. iPod, iTunes, iPhone…need I say more?
6. Chad Hurley, Steve Chen and Jawed Karim

Chad, Steve and Jawed, who were all early employees of founded YouTube in 2005. By making the video-sharing process much easier and simple, YouTube revolutionized the way users uploaded, viewed and shared video clips.
7. Chris DeWolfe and Tom Anderson

Chris and Tom founded MySpace in August 2003. MySpace is currently the largest social-networking website and is credited for beginning the wild-social-networking-craze even though Facebook has been gaining popularity at a much faster pace recently.
8. Jason Calacanis

Jason is CEO and co-founder of Weblogs Inc., a network of widely read blogs. He generated a lot of buzz in the blogosphere when he sold his network of blogs to AOL for $25 million in 2005.
9. Markus Frind

Markus is widely known for single-handedly running the dating-site Plenty Of Fish. He often gets quoted when people talk about adsense earnings. According to this article, his site is on track to bring in over $10 million in revenue next year - that is over $30,000 per day.
10. Alex Tew

The Million Dollar Homepage was founded by Alex Tew, a 21-year-old student from England, to help raise money for his university education. The website is said to have generated a gross income of $1,037,100 USD by selling one million pixels on the homepage of the site for $1 each. His success sparked a number of other similar sites selling words, links, wiki pages and anything else you can think of.